2-Picolinic Acid CAS 98-98-6

1. 2-Picolinic acid is widely utilized as a versatile building block in pharmaceutical development, serving as a key intermediate in the synthesis of BACE 2 inhibitors for diabetes treatment and other therapeutic agents .
2. 2-Picolinic acid CAS 98-98-6 functions as an effective chelating agent for metal ions, forming stable picolinato-ligated transition metal complexes used in coordination chemistry and environmental applications for removing heavy metals from wastewater .
3. 2-Picolinic acid is employed as an important immunomodulator in plants and humans, and serves as a reagent in organic synthesis, participating in reactions such as the Mitsunobu reaction and the Hammick reaction .
4. Researchers utilize 2-Picolinic acid CAS 98-98-6 as a substrate in synthetic organic chemistry and as a building block in agrochemical formulations for improving the effectiveness of herbicides and pesticides .

1. 2-Picolinic acid must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment; powder is stable for up to 2 years at 2-8°C, while solutions should be stored at -20°C for up to 1 month .
2. 2-Picolinic acid CAS 98-98-6 is classified with GHS hazard statements H302 (Harmful if swallowed) and H318 (Causes serious eye damage), with signal word "Danger" according to safety data sheets .
3. Personnel must wear chemical-resistant rubber gloves, chemical safety goggles, and protective clothing when handling 2-picolinic acid, as it causes skin, eye, and respiratory tract irritation .
4. Keep away from incompatible materials such as strong oxidizing agents, reducing agents, acids, and bases; avoid dust formation and store separately from ignition sources .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including NIOSH/MSHA-approved respirator, chemical-resistant gloves, and safety goggles when 2-picolinic acid is released .
2. Collect 2-Picolinic acid CAS 98-98-6 by sweeping or vacuuming without creating dust using non-sparking tools; for solutions, absorb with finely-powdered liquid-binding materials such as diatomite or universal binders .
3. Decontaminate surfaces and equipment by scrubbing with alcohol; avoid creating dust clouds during cleanup to prevent respiratory exposure .
4. Dispose of collected material according to local, state, and federal environmental regulations; the substance is considered non-hazardous for transport but should be treated as hazardous waste .

1. 2-Picolinic acid is combustible with a flash point of 139°C (282°F); under fire conditions, hazardous decomposition products include toxic fumes of carbon monoxide, carbon dioxide, and nitrogen oxides (NOx) .
2. Use water spray, dry chemical powder, carbon dioxide, or alcohol-resistant foam to extinguish fires involving the product; do NOT use a direct water jet as 2-Picolinic acid CAS 98-98-6 may scatter burning material .
3. Firefighters should wear self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved, and full protective gear when handling burning 2-picolinic acid due to hazardous decomposition gases generated by thermal decomposition .
4. During combustion, may emit irritant and toxic fumes; move containers from the fire area if safe to do so, cool exposed containers with water spray from a protected location, and contain fire runoff to prevent environmental contamination .