Phosphatidylserine CAS 51446-62-9

1. Phosphatidylserine is a natural phospholipid used as a functional food ingredient and dietary supplement for its significant nutritional and biological functions, including improving memory, preventing Alzheimer's dementia, decreasing stress, and increasing attention .
2. Phosphatidylserine CAS 51446-62-9 serves as a key component in liposomal formulations for drug delivery systems, where it can be anionic, cationic, or neutral in charge, and is used in PEGylated forms (phosphatidylserine PEG) to improve circulation time and stability for encapsulated drugs, gene transfection, and vaccine delivery .
3. Phosphatidylserine is widely utilized in the cosmetic and pharmaceutical industries, and research focuses on its enzymatic synthesis via phospholipase D (PLD) biocatalysis, with immobilized PLD achieving high conversion yields and excellent reusability for industrial production .
4. The compound is incorporated into liposomes and vesicles for physical stability studies, with formulations containing phosphatidylserine demonstrating improved stability compared to other lipid compositions when stored at 4°C .

1. Phosphatidylserine must be stored in a tightly sealed container at -20°C, protected from light and heat; under these conditions, the solid state is stable, and chloroform or dichloromethane solutions are also stable .
2. Phosphatidylserine CAS 51446-62-9 is stable when protected from oxygen, heat, and light; liposomal formulations can degrade via oxidation and hydrolysis, and minimizing oxygen exposure and adding antioxidants such as butylated hydroxytoluene (BHT) can reduce oxidation .
3. Personnel must wear chemical-resistant rubber gloves, chemical safety goggles with side-shields, and protective clothing when handling this substance, ensuring adequate ventilation and avoiding dust and aerosol formation .
4. Keep away from incompatible materials such as strong acids/alkalis and strong oxidizing/reducing agents; for solution storage, prepare aliquots and avoid repeated freeze-thaw cycles to prevent degradation .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and suitable respirator when Phosphatidylserine is released .
2. For Phosphatidylserine CAS 51446-62-9 spills, absorb solutions with finely-powdered liquid-binding materials such as diatomite or universal binders; for solid spills, sweep or vacuum without creating dust using non-sparking tools, and place into suitable closed containers for disposal .
3. Decontaminate surfaces and equipment by scrubbing with alcohol; avoid creating dust clouds during cleanup to prevent respiratory exposure .
4. Prevent the product from entering drains, water courses, or the soil, as runoff from fire control or dilution water may cause pollution; dispose of collected material according to local, state, and federal environmental regulations .

1. Phosphatidylserine is not classified as highly flammable but may decompose under fire conditions, emitting irritant fumes; use water spray, dry chemical powder, foam, or carbon dioxide to extinguish fires involving the product .
2. During Phosphatidylserine CAS 51446-62-9 combustion, may emit irritant and toxic fumes; firefighters should wear self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved, and full protective gear .
3. Keep containers tightly sealed and store away from direct sunlight and sources of ignition; the product is stable under recommended storage conditions .
4. Hazardous decomposition products formed under fire conditions may include toxic fumes; contain fire runoff to prevent environmental contamination .